Skip to main content

Table 12 Model parameters

From: Validation of a yellow fever vaccine model using data from primary vaccination in children and adults, re-vaccination and dose-response in adults and studies with immunocompromised individuals

Parameter Unit Value
\(\pi _v\) (day\(^{-1}\)) \(6.80 \times 10^{-1}\)
\(c_{v1}\) (day\(^{-1}\)) \(2.63 \times 10^{0}\)
\(c_{v2}\) (copies/mL) \(6 \times 10^{-1}\)
\(k_{v1}\) [day\(^{-1}\) (mIU/mL)\(^{-1}\)] \(4.82 \times 10^{-5}\)
\(k_{v2}\) [day\(^{-1}\) (cells/mL)\(^{-1}\)] \(7.48 \times 10^{-7}\)
\(\alpha _{ap}\) (day\(^{-1}\)) \(2.5 \times 10^{-3}\)
\(\beta _{ap}\) [day\(^{-1}\) (copies/mL) \(^{-1}\)] \(5.5 \times 10^{-1}\)
\(c_{ap1}\) (copies/mL) \(8 \times 10^{-1}\)
\(c_{ap2}\) (copies/mL) \(4 \times 10^{1}\)
\(\delta _{apm}\) (day\(^{-1}\)) \(5.38 \times 10^{-1}\)
\(\alpha _{th}\) (day\(^{-1}\)) \(2.17 \times 10^{-4}\)
\(\beta _{th}\) (day\(^{-1}\)) \(1 \times 10^{-7}\)
\(\pi _{th}\) (day\(^{-1}\)) \(1 \times 10^{-8}\)
\(\delta _{th}\) (day\(^{-1}\)) \(2.2 \times 10^{-1}\)
\(\alpha _{tk}\) (day\(^{-1}\)) \(2.17 \times 10^{-4}\)
\(\beta _{tk}\) (day\(^{-1}\)) \(1 \times 10^{-5}\)
\(\pi _{tk}\) (day\(^{-1}\)) \(1 \times 10^{-8}\)
\(\delta _{tk}\) (day\(^{-1}\)) \(3 \times 10^{-4}\)
\(\alpha _{b}\) (day\(^{-1}\)) \(6.0 \times 10^{0}\)
\(\pi _{b1}\) (day\(^{-1}\)) \(4.83 \times 10^{-6}\)
\(\pi _{b2}\) (day\(^{-1}\)) \(1.27 \times 10^{-8}\)
\(\beta _{ps}\) (day\(^{-1}\)) \(6.72 \times 10^{-4}\)
\(\beta _{pl}\) (day\(^{-1}\)) \(5.61 \times 10^{-6}\)
\(\beta _{bm}\) (day\(^{-1}\)) \(1 \times 10^{-6}\)
\(\delta _{ps}\) (day\(^{-1}\)) \(2.0 \times 10^{0}\)
\(\delta _{pl}\) (day\(^{-1}\)) \(2.4 \times 10^{-4}\)
\(\gamma _{bm}\) (day\(^{-1}\)) \(9.75 \times 10^{-4}\)
\(\pi _{bm1}\) (day\(^{-1}\)) \(1 \times 10^{-5}\)
\(\pi _{bm2}\) (cells/mL) \(2.5 \times 10^{3}\)
\(\pi _{ps}\) (day\(^{-1}\)) \(2 \times 10^{-3}\)
\(\pi _{pl}\) (day\(^{-1}\)) \(6.8 \times 10^{-4}\)
\(\delta _a\) (day\(^{-1}\)) \(4 \times 10^{-2}\)