Table 12 Model parameters

\(\pi _v\)

(day\(^{-1}\))

\(6.80 \times 10^{-1}\)

\(c_{v1}\)

(day\(^{-1}\))

\(2.63 \times 10^{0}\)

\(c_{v2}\)

(copies/mL)

\(6 \times 10^{-1}\)

\(k_{v1}\)

[day\(^{-1}\) (mIU/mL)\(^{-1}\)]

\(4.82 \times 10^{-5}\)

\(k_{v2}\)

[day\(^{-1}\) (cells/mL)\(^{-1}\)]

\(7.48 \times 10^{-7}\)

\(\alpha _{ap}\)

(day\(^{-1}\))

\(2.5 \times 10^{-3}\)

\(\beta _{ap}\)

[day\(^{-1}\) (copies/mL) \(^{-1}\)]

\(5.5 \times 10^{-1}\)

\(c_{ap1}\)

(copies/mL)

\(8 \times 10^{-1}\)

\(c_{ap2}\)

(copies/mL)

\(4 \times 10^{1}\)

\(\delta _{apm}\)

(day\(^{-1}\))

\(5.38 \times 10^{-1}\)

\(\alpha _{th}\)

(day\(^{-1}\))

\(2.17 \times 10^{-4}\)

\(\beta _{th}\)

(day\(^{-1}\))

\(1 \times 10^{-7}\)

\(\pi _{th}\)

(day\(^{-1}\))

\(1 \times 10^{-8}\)

\(\delta _{th}\)

(day\(^{-1}\))

\(2.2 \times 10^{-1}\)

\(\alpha _{tk}\)

(day\(^{-1}\))

\(2.17 \times 10^{-4}\)

\(\beta _{tk}\)

(day\(^{-1}\))

\(1 \times 10^{-5}\)

\(\pi _{tk}\)

(day\(^{-1}\))

\(1 \times 10^{-8}\)

\(\delta _{tk}\)

(day\(^{-1}\))

\(3 \times 10^{-4}\)

\(\alpha _{b}\)

(day\(^{-1}\))

\(6.0 \times 10^{0}\)

\(\pi _{b1}\)

(day\(^{-1}\))

\(4.83 \times 10^{-6}\)

\(\pi _{b2}\)

(day\(^{-1}\))

\(1.27 \times 10^{-8}\)

\(\beta _{ps}\)

(day\(^{-1}\))

\(6.72 \times 10^{-4}\)

\(\beta _{pl}\)

(day\(^{-1}\))

\(5.61 \times 10^{-6}\)

\(\beta _{bm}\)

(day\(^{-1}\))

\(1 \times 10^{-6}\)

\(\delta _{ps}\)

(day\(^{-1}\))

\(2.0 \times 10^{0}\)

\(\delta _{pl}\)

(day\(^{-1}\))

\(2.4 \times 10^{-4}\)

\(\gamma _{bm}\)

(day\(^{-1}\))

\(9.75 \times 10^{-4}\)

\(\pi _{bm1}\)

(day\(^{-1}\))

\(1 \times 10^{-5}\)

\(\pi _{bm2}\)

(cells/mL)

\(2.5 \times 10^{3}\)

\(\pi _{ps}\)

(day\(^{-1}\))

\(2 \times 10^{-3}\)

\(\pi _{pl}\)

(day\(^{-1}\))

\(6.8 \times 10^{-4}\)

\(\delta _a\)

(day\(^{-1}\))

\(4 \times 10^{-2}\)