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Table 5 Average c-index values of the proposed model and random forest model using different amount of training data. The mean c-index was obtained by randomly selecting the training and test dataset 50 times

From: Investigating the relevance of major signaling pathways in cancer survival using a biologically meaningful deep learning model

Ratio of training data (%)

Proposed model

Random forest model

Mean c_index on training data

Mean c_index on test data

Mean c_index on training data

Mean c_index on test data

GBM

50

0.6672

0.5869

0.7202

0.5383

60

0.6630

0.6033

0.7034

0.5404

70

0.6745

0.6029

0.6982

0.5450

80

0.6568

0.6085

0.6936

0.5493

90

0.6636

0.6392

0.6929

0.5612

SKCM

50

0.7959

0.6961

0.7975

0.5178

60

0.7576

0.6680

0.7879

0.5237

70

0.7209

0.6950

0.7751

0.5277

80

0.7685

0.6717

0.7653

0.5255

90

0.7246

0.6643

0.7541

0.5208

BRCA

    

50

0.6235

0.5435

0.8356

0.5217

60

0.6723

0.5768

0.8298

0.5262

70

0.6942

0.5627

0.8222

0.5154

80

0.7038

0.5835

0.8075

0.5026

90

0.7076

0.6157

0.8069

0.5036

LUAD

50

0.7043

0.5857

0.8486

0.5641

60

0.7345

0.6708

0.8294

0.5702

70

0.6954

0.6363

0.8187

0.5704

80

0.7560

0.7249

0.8088

0.5809

90

0.7394

0.7419

0.8020

0.5822