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Fig. 5 | BMC Bioinformatics

Fig. 5

From: A computational diffusion model to study antibody transport within reconstructed tumor microenvironments

Fig. 5

Example of a tuned stochastic computational capsule with and without fibers. Simulation with Dmedium = 0.15 μm2/s, Dcell = 0.0015 μm2/s, a = 1, n = 1, and p = 1, for two scenarious: i without fibers and ii with fibers. a Graphical representation of one random tuned capsule, with the indication of the selected clusters; b Initial diffusivity coefficients throughout the capsule; cd Antibody concentration for two different time points (30 and 180 min, respectively); e Antibody concentration profile for the three cell clusters identified in a (blue—cluster 1, orange—cluster 2, green—cluster 3); scale bar: 100 µm

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