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Fig. 4 | BMC Bioinformatics

Fig. 4

From: TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

Fig. 4

Immunogenic neoantigens of patient 01 predicted by TruNeo and MHCflurry validated by Elispot assays. We have predicted the top10 MHC class I neoantigens for patient01 by TruNeon and MHCflurry. According the rank of the neoantigens were labeled as #1–#10, the immunogenicity of the neoantigen peptides predicted by two models have been validated by the Elispot assay. #1, #3, #4, #6, #8 of the top 10 neoantigen predicted by TruNeo were Elispot positive; #5, #6 of the top 10 neoantigen predicted by MHCflurry were Elispot positive

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