Fig. 1
From: SCC: an accurate imputation method for scRNA-seq dropouts based on a mixture model
The bimodal expression distribution. The typical bimodal expression distribution of scRNA-seq data (The eleventh gene in mECS, which is a dataset about mammary epithelial cells). The detection rate of mRNA is 5–15%. The genes with low expression levels are difficult to detect. Therefore, the expression of scRNA-seq data is either strongly zero or high expression. We call this distribution a bimodal distribution