TY - JOUR AU - Zhou, Linjun AU - Fan, Deling AU - Yin, Wei AU - Gu, Wen AU - Wang, Zhen AU - Liu, Jining AU - Xu, Yanhua AU - Shi, Lili AU - Liu, Mingqing AU - Ji, Guixiang PY - 2021 DA - 2021/03/24 TI - Comparison of seven in silico tools for evaluating of daphnia and fish acute toxicity: case study on Chinese Priority Controlled Chemicals and new chemicals JO - BMC Bioinformatics SP - 151 VL - 22 IS - 1 AB - A number of predictive models for aquatic toxicity are available, however, the accuracy and extent of easy to use of these in silico tools in risk assessment still need further studied. This study evaluated the performance of seven in silico tools to daphnia and fish: ECOSAR, T.E.S.T., Danish QSAR Database, VEGA, KATE, Read Across and Trent Analysis. 37 Priority Controlled Chemicals in China (PCCs) and 92 New Chemicals (NCs) were used as validation dataset. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-020-03903-w DO - 10.1186/s12859-020-03903-w ID - Zhou2021 ER -