Chemicals | Methods | Measures of predictive performance | ECOSAR | T.E.S.T. | Danish Q.D. | VEGA | Read Across | Trend Analysis | KATE |
---|---|---|---|---|---|---|---|---|---|
37 PCCs | Number of missing predictions | 0 | 4 | 3 | 2 | 2 | 6 | 12 | |
Qualitative | Number of correct | 24 | 21 | 20 | 18 | 16 | 14 | 21 | |
Number of incorrect | 13 | 12 | 14 | 17 | 19 | 17 | 4 | ||
Total accuracy (%)a | 65 | 64 | 59 | 51 | 46 | 45 | 84 | ||
Predictive power (%)b | 65 | 57 | 54 | 49 | 43 | 38 | 57 | ||
R2 (toxicity class) | 0.46 | 0.46 | 0.37 | 0.29 | 0.51 | 0.33 | 0.65 | ||
Quantitative | Accuracy within a factor of 10 (%) | 76 | 67 | 68 | 63 | 49 | 45 | 80 | |
Accuracy within a factor of 100 (%) | 86 | 91 | 91 | 80 | 83 | 55 | 96 | ||
Accuracy within a factor of 1000 (%) | 97 | 97 | 94 | 94 | 94 | 81 | 100 | ||
R2(log10 LC50) | 0.40 | 0.42 | 0.38 | 0.13 | 0.42 | 0.40 | 0.68 | ||
42 NCs | Qualitative | Number of correct | 22 | 9 | 13 | 9 | /c | / | 9 |
Number of incorrect | 16 | 22 | 11 | 32 | / | / | 11 | ||
Number of missing predictions | 4 | 11 | 18 | 1 | / | / | 22 | ||
Total accuracy (%)a | 58 | 29 | 54 | 22 | / | / | 45 | ||
Predictive power (%)b | 52 | 21 | 31 | 21 | / | / | 21 | ||
R2 (toxicity class) | 0.35 | 0.04 | 0.50 | 0.04 | / | / | 0.36 |