Chemicals | Methods | Measures of predictive accuracy | ECOSAR | T.E.S.T | Danish Q.D. | VEGA | Read Across | Trend Analysis | KATE |
---|---|---|---|---|---|---|---|---|---|
37 PCCs | Number of missing predictions | 0 | 2 | 3 | 1 | 2 | 4 | 9 | |
Qualitative | Number of correct | 20 | 17 | 17 | 17 | 14 | 10 | 10 | |
Number of incorrect | 17 | 18 | 17 | 19 | 21 | 23 | 18 | ||
Total accuracy (%)a | 54 | 49 | 50 | 47 | 40 | 30 | 36 | ||
Predictive power (%)b | 54 | 46 | 46 | 46 | 38 | 27 | 27 | ||
R2 (toxicity class) | 0.50 | 0.39 | 0.38 | 0.43 | 0.17 | 0.10 | 0.25 | ||
Quantitative | Accuracy within a factor of 10 (%) | 68 | 80 | 65 | 81 | 57 | 36 | 71 | |
Accuracy within a factor of 100 (%) | 89 | 89 | 79 | 94 | 83 | 48 | 86 | ||
Accuracy within a factor of 1000 (%) | 92 | 97 | 85 | 97 | 94 | 76 | 89 | ||
R2(log10 LC50) | 0.31 | 0.35 | 0.27 | 0.34 | 0.32 | 0.03 | 0.21 | ||
86 NCs | Qualitative | Number of correct | 34 | 25 | 17 | 18 | / | / | 17 |
Number of incorrect | 47 | 36 | 24 | 65 | / | / | 40 | ||
Number of missing predictions | 5 | 25 | 45 | 3 | / | / | 29 | ||
Total accuracy (%)a | 42 | 41 | 41 | 22 | / | / | 30 | ||
Predictive power (%)b | 40 | 29 | 20 | 21 | / | / | 20 | ||
R2 (toxicity class) | 0.08 | 0.10 | 0.13 | 0.001 | / | / | 0.03 |