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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data

Fig. 4

The performance of Accucopy in predicting TCNs for TCGA samples. CallF and FullC were calculated to assess the performance of Accucopy. Each dot represents one TCGA sample and is colored according to its sequencing coverage. Each scatterplot is fitted with a redline by loess smoothing. a FullC is between 0.3 and 0.9, strongly dependent on the tumor purity level. b CallF is between 0.93 and 0.96, independent of the tumor purity level, indicating Accucopy predicted copy numbers for almost the entire genome for all analyzed TCGA samples. c FullC is independent of CallF. d The colorbar maps the sequencing coverage of each sample to the color of each dot. The sequencing coverage is set to 10 for samples with sequencing coverage above 10

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BMC Bioinformatics

ISSN: 1471-2105

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