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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Boolean implication analysis unveils candidate universal relationships in microbiome data

Fig. 1

Study design. The overview of the research process: a OTU tables were collected from publicly available microbiome datasets. b Tables were uploaded to Hegemon and all possible microbe pairs were plotted (using 4 plots as examples—the number of total plots is larger). c Boolean analysis was performed on all the plots. d The plots that passed the BooleanNet statistics tests were marked as candidate invariants for further analysis and validation. e Any of the determined candidates that can be validated in other datasets, represents a likely universal invariant (a rule between two microbes that holds between them, any time the pair are present together in any environment). *Note that this is just an example. A universal invariant can be any of the 6 possible Boolean relationship

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