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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Drug-induced cell viability prediction from LINCS-L1000 through WRFEN-XGBoost algorithm

Fig. 1

LINCS-L1000 and CTRP, Achilles data association diagram. The process of data association consisted of two parts: perturbation signatures and cell phenotypic information. The LINCS-L1000-PhaseI and LINCS-L1000-PhaseII were combined and renamed LINCS-L1000. The compound perturbation signatures and shRNA perturbation signatures involved in LINCS-L1000 were respectively associated with CTRP and Achilles datasets according to relevant conditions, which were named CTRP-L1000 and Achilles-L1000. The datasets were divided into CTRP-L1000-3h, CTRP-L1000-6h, CTRP-L1000-24h, Achilles-L1000-96h, Achilles-L1000-120h and Achilles-L1000-144h according to different perturbation time. CTRP-L1000-3h, CTRP-L1000-6h, and CTRP-L1000-24h were divided into six subsets according to the concentration factor was considered(S2) or not considered(S1)

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