Fig. 1
From: Detection of suspicious interactions of spiking covariates in methylation data
Top 6 of the reverse negative or negation CpG sites of the data set E-GEOD-54643. The order was determined by the effect deviation between the coefficients from two linear regressions, one associated with all data included and one with exclusion of the spike associated data. The spike at right increases the regression line. Without the spike the regression effect would be negative, including the spike at right the regression effect becomes positive. A biologist has to decide, if the CpG sites are biological connected or can be seen as outlier. Table 2 shows the position and genes nearby of the CpG sites