Fig. 4

Clusters of significant variants at different frequencies. Multiple variants of significant association were found at clusters of different allele frequencies, suggesting clusters of variants carried together through linkage disequilibrium. This pattern is only visible in three dimensions (right, fig. 4b) and not when looking straight down the axis (left, fig. 4a) as one would in a regular 2-dimensional Manhattan plot. Numbers on the panels in the figure indicate the chromosome(s) being viewed