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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Identifying glycan motifs using a novel subtree mining approach

Fig. 5

Predicted carbohydrate-binding motifs of RCA I from CFG glycan microarray data. a Distribution of RFUs and classification of non-binding (blue), intermediate binding (orange), and binding glycans (red). b ROC curves for the test (n=125) and training (n=372) sets. The ratio of negative to positive samples was 4.4. c Logistic regression coefficients for identified motifs. d The intermolecular hydrogen bonding interactions (shown in green) between β-galactose (carbon backbone shown in yellow) and the carbohydrate-binding domain of the B chain of ricin (carbon backbones shown in grey). Reproduced from an X-ray crystal structure at 2.5 Å resolution available at the PDB (PDB: 3RTI) [39]. See Additional file 1 for a detailed notation key

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