Fig. 2
From: MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering
a Pareto-optimal points obtained upon simulation of yeast alcoholic fermentation maximizing biomass and ethanol production. The fluxes obtained for ethanol and biomass production on the A-G points of the Pareto frontier are as follows: A(8.8;0.43); B(11.8;0.41);C(15.3;0.27);D(17.2;0.19);E(17.4;0.18); F(17.5;0.17); G(19.8;0.0). b Heatmap illustrating the difference of the fluxes between the wild-type and mutants corresponding to each Pareto point. Considering reactions related to glycerol production, glycolysis, TCA cycle, and ethanol production and utilization