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Table 2 The mean wall-clock time (from 3 runs) that MOMO took to run the FBA (step 1), BOP (step 3) with two objectives and the enumeration procedure for K=1,2,3 for the point G of the Pareto front of Fig. 2 just to illustrate the difficulty of the problems

From: MOMO - multi-objective metabolic mixed integer optimization: application to yeast strain engineering

ProblemTime (s)
Enumeration K= 1470.3
Enumeration K= 21712.6
Enumeration K= 3>604800.0
  1. For K=3 the program did not finish before the time-out of one weeK (604800s)