Fig. 1
From: Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
Schematic of the Model. The crypt model comprises a biomechanical model (the voronoi tessellation model found in Chaste) and a suitable biochemical model specified in SBML. The biochemical model specifies adhesion and cell proliferation in the biomechanical model which leads to cell movement in the crypt model. Cell phenotype (mutation level) and Wnt concentration are provided to the biochemical model by the biomechanical and crypt models respectively. SBML logo reproduced with permission from http://www.sbml.org