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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt

Fig. 3

Drag functions. Drag as a function of the level of complex in the cytosol/membrane (CA in the VL model and NC in the Tan model). The lower γ, the higher the drag. I.e. for mutant cells the amount of complex in the cytosol/membrane increases, as seen in Fig. 8, and we assume that this increases the drag. Also when the Wnt signal is higher, the drag will be higher for γ≠0 (as the amount of complex is higher). Arrows are drawn in the direction of increasing γ. The cases are shown for γ=0−1 in increments of 0.1 (γ=0 is red, γ=1 is blue)

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