Fig. 8
From: Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
The effect of varying the expression of the APC mutation parameter, γ, on the bound complexes in the nucleus and cytosol-membrane. For the VL (top) and Tan models (bottom). Arrows are drawn in the direction of increasing γ. Decreasing γ increases the amount of bound complexes in both the complexes for adhesion and transcription. The cases are shown for γ=0−1 in increments of 0.1 (γ=0 is red, γ=1 is blue)