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Table 5 AUC of the evaluated CNV callers on the TCGA prostate dataset

From: CNV Radar: an improved method for somatic copy number alteration characterization in oncology

Caller

AUC (gain)

AUC (loss)

CNV Radar

0.75

0.83

CNVkit

0.75

0.86

CoNIFER_FCSVD0

0.62

0.53

CoNIFER_FCSVD1

0.59

0.52

CoNIFER_FCSVD2

0.37

0.38

CoNIFER_FCSVD3

0.14

0.26

CopywriteR

0.26

0.21

ExomeDepth

0.25

0.24

  1. AUC area under the receiver operating characteristic curve; CNV copy number variation; TCGA The Cancer Genome Atlas; Radar rapid aberration detection and reporting; CoNIFER copy number inference from exome reads