Skip to main content
Fig. 8 | BMC Bioinformatics

Fig. 8

From: Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

Fig. 8

Comparison of the clustering of the conserved residues within the real interface and other random surface patches for the assembly of the SXL-UNR translation regulatory complex (PDB code: 4qqb). (a) Distributions of the conserved and the remaining residues at the real protein interface. In the first panel, RNA is in yellow and in the other two, it is removed to clearly show the clustering property of the conserved residues within the interface from different views. (b) The scheme of generating random surface patches with method 1 mentioned in materials and methods: a surface residue (represented by its Ca atom) is taken randomly as a center and then all the surface residues within 20 Å (half of the mean maximum distance 40 Å between any two atoms of all the interfaces) away from the center are chosen as belonging to the surface patch (yellow) with the taken residue as the center. (c) Distributions of the conserved and remaining residues at sixteen different random surface patches, where the conserved ones are relatively scattered over the random surface patch compared with those at the real interface. Protein is shown in CPK (grey), the conserved residues are in green and non-conserved ones in blue

Back to article page