Analyses on clustering of the conserved residues at protein-RNA interfaces and its application in binding site identification

Table 2 Parameters describing the clustering of conserved interface residues

Criteria of conserved residues	Average^a			Num of interfaces^b
Criteria of conserved residues	M_s,int	M_s,cons	ρ	Total	with M_s,cons > M_s,int
s < <s > _int	0.082 (0.03)	0.087 (0.03)	1.06 (0.10)	180	140
s < (<s > _int/2)	0.080 (0.03)	0.088 (0.03)	1.11 (0.18)	172	135
s = 0.0	0.078 (0.03)	0.087 (0.03)	1.15 (0.28)	150	114

^a Standard deviations are in parentheses
^b A smaller number of interfaces is obtained when using more stringent definitions of conserved residues

ISSN: 1471-2105