Table 3 Distribution of 139 alanine scanned interface residues among the seven amino acid classes
Amino acid class | Num in entire dataset | Num of hot spot residues (ΔΔG ≥ 2.0 kcal/mol) | percentage of hot spot residues |
|---|---|---|---|
Ala, Val, Leu, Ile, Met, Cys | 3 | 1 | 33.33% |
Gly, Ser, Thr | 19 | 3 | 15.79% |
Asp, Glu | 16 | 1 | 6.25% |
Asn, Gln | 18 | 1 | 5.56% |
Arg, Lys | 49 | 10 | 20.41% |
Pro, Phe, Tyr, Trp | 27 | 16 | 59.26% |
His | 7 | 1 | 14.29% |