Fig. 5
From: A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA
Systematic evaluation of the effectiveness of all filters. a, b Fraction of panel-wide error-free positions in the 14 Oncosmart2 controls and 11 Oncosmart2 RSDs obtained with each filter. c Numbers of false-positive sites retained among 11 Oncosmart2 RSDs. d–h Panel-wide sensitivity and PPVs obtained with our algorithm (red circles) and five published calling algorithms using Oncosmart2 RSDs with AF values ranging from 0.1 to 5%