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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington’s disease mice

Fig. 3

Selected miRNA-target pairs in the cortex of Hdh mice. Shown are the 9 miRAMINT miRNA-target pairs (see also Table S3 for the full list of miRAMINT miRNA-target pairs in cortex). The targets are contained in rectangles and the miRNAs in ellipses. A thick edge means that evidence for binding sites is available from at least two miRNA databases. A thin edge means that evidence for binding sites is available from only one miRNA database. All LFC are below 0.5. A cross arrow indicates the miRNA that is best paired with a target when this target has several possible miRNA regulators. Biological annotations of miRNA targets correspond to GO Biological processes or KEGG pathways at the result of STRING analyzes using stringent criteria (i.e. STRING score > 0.7, Databases and Experiments only, 5 neighbors added on the first shell) the KEGG pathways are those with, at

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BMC Bioinformatics

ISSN: 1471-2105

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