From: Comparative study of whole exome sequencing-based copy number variation detection tools
Tools | Language | Input format | Methodology | Installation tutorial | Reference |
---|---|---|---|---|---|
CoNIFER | python | BAM/RPKM、bed、RPKM | Principal Component Analysis | Krumm. et al.(2012) [17] | |
exomeCopy | R | BAM、bed、Grange | A hidden Markov model which uses positional covariates | http://www.bioconductor.org/packages/release/bioc/html/exomeCopy.html | Love. et al.(2011) [18] |
CNVkit | python | BAM、bed、cnn | Principal Component Analysis | Eric. et al.(2016) [19] | |
cn.MOPS | R | BAM、bed、Grange | Bayesian approach | Klambauer. et al.(2012) [20] |