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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Variant effect predictions capture some aspects of deep mutational scanning experiments

Fig. 3

Experimental agreement vs. predictions. For every pair of experimental measurements on the same protein (Table S1), the agreement between two experiments and that between each experiment and the predictions of SNAP2 and Naïve Conservation are compared. a ∆ρ = 0.5*(ρ(× 1,p1) + ρ(× 2,p2)) - ρ(× 1,× 2), (b) ∆MSE = MSE(× 1,× 2) - 0.5*(MSE(× 1,p1) + MSE(× 2,p2)). Where × 1/× 2 are the experiments and p1/p2 the predictions on the two experiments, all of which are calculated based on the largest possible set of SAVs. Negative values on the y-axes thus imply that the agreement between experiments is higher than that between experiment and prediction, positive values that predictions agree more

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