Fig. 3From: Intrinsic limitations in mainstream methods of identifying network motifs in biologyNon-reproducibility of the switching method. Frequency distributions of the number of copies nS(Z) of the motif-candidate Z found in networks similar to the E. coli TF network, as approximated by drawing 10,000 comparison networks from \( \mathbbm{S}(G) \), generated using the switching method. Each of the four histograms is computed from a separate run of the algorithm, using the same candidate motif and the same input network. The actual frequency nG(Z) of the candidate motif Z in the original network is also shown, for comparisonBack to article page