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Fig. 9 | BMC Bioinformatics

Fig. 9

From: ppiGReMLIN: a graph mining based detection of conserved structural arrangements in protein-protein interfaces

Fig. 9

Critical interactions for the BCL-2/BH3 binding. Critical residue interactions are shown in the structure of the Bcl-XL:Beclin 1 complex (PDB id 2P1L). The Beclin 1 chain, a BH3 only protein, is shown in orange in the hydrophobic groove of Bcl-xL, an anti apoptotic protein. Hydrophobic interactions are depicted by dashed lines in blue, salt bridges in green, and hydrogen bonds in orange. The five interacting residues from BH3 chain represent those found in patterns and in literature

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BMC Bioinformatics

ISSN: 1471-2105

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