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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes

Fig. 3

CNAtra validation of well-known LCVs and FAs. a CNAtra correctly detects the large segmental aneuploidies of Chr 16 (top) and Chr 17 (bottom) of HepG2 cell line described earlier using array CGH (shown as red bars below the idiograms). The black bar denotes the centromere region while the white bar represents CN-neutral (2N) region. b CNAtra identifies monoallelic 1p deletion in both IMR-32 and CHP-212 neuroblastoma cells. c CNAtra detects focal amplifications (MYC and MYCN loci) and focal deletions (BANK1/4q24 and LKB1/STK11 loci) in respective cancer cell lines

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BMC Bioinformatics

ISSN: 1471-2105

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