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Table 1 The PEP estimation errors of three methods on the simulated data

From: Transfer posterior error probability estimation for peptide identification

 

Method

Ratio=1%

Ratio=5%

Ratio=10%

Ratio=20%

Ratio=100%

  

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

n=1

Combined

71.88

4.53

33.75

3.08

19.75

1.89

10.71

1.02

2.27

0.20

 

Separate

7.02

5.67

1.81

1.46

0.98

0.80

0.52

0.43

0.11

0.09

 

Transfer

4.33

4.14

1.21

1.14

0.68

0.64

0.37

0.35

0.08

0.08

n=10

Combined

56.71

3.54

31.91

2.75

18.93

1.76

10.31

0.96

2.19

0.19

 

Separate

4.86

4.20

1.38

1.20

0.76

0.66

0.41

0.36

0.09

0.08

 

Transfer

2.78

2.70

0.89

0.90

0.51

0.52

0.28

0.29

0.06

0.06

n=20

Combined

41.11

3.75

29.73

2.59

18.00

1.74

9.87

0.98

2.11

0.19

 

Separate

3.78

3.41

1.24

1.13

0.70

0.65

0.38

0.36

0.08

0.08

 

Transfer

2.00

1.88

0.76

0.81

0.46

0.49

0.26

0.28

0.06

0.06

n=50

Combined

8.41

3.62

25.67

2.14

16.36

1.53

9.10

0.86

1.95

0.17

 

Separate

2.04

1.51

1.02

0.90

0.59

0.54

0.33

0.31

0.07

0.07

 

Transfer

1.01

0.81

0.66

0.70

0.41

0.44

0.23

0.26

0.05

0.06

n=100

Combined

0.03

0.05

19.10

1.68

13.77

1.36

7.87

0.78

1.70

0.15

 

Separate

0.13

0.23

0.80

0.66

0.47

0.41

0.26

0.23

0.06

0.05

 

Transfer

0.05

0.07

0.49

0.50

0.32

0.35

0.19

0.21

0.04

0.05

  1. Notes: Mean and SD, the mean and standard deviation of mean squared errors (MSEs) of estimates; n, the number of correct scores in group G; Ratio, the percentage of top scores whose MSEs were evaluated