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Table 2 Performance comparisons of different methods on D92M over leave-one-out cross-validation. The best results for each metric are in bold

From: Identifying GPCR-drug interaction based on wordbook learning from sequences

Method

Sn (%)

Sp (%)

Acc (%)

Str(%)

MCC

iGPCR-Drug

78.3

91.4

86.9

84.9

0.71

OET-KNN

77.8

88.7

85.0

83.3

0.67

QuickRBF

74.8

92.4

86.4

83.6

0.69

SVM

74.2

92.7

86.3

83.5

0.69

RF

76.5

92.9

87.3

84.7

0.71

RF + PPP

79.7

92.8

88.3

86.3

0.73

Proposed(Base learner)

81.4

84.7

83.6

83.1

0.64

Proposed(Ensemble model with Ne = 4)

81.1

87.1

85.1

84.1

0.67