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Table 3 Performance comparisons of different methods on the independent test dataset check390. The best results for each metric are in bold

From: Identifying GPCR-drug interaction based on wordbook learning from sequences

Method

Sn (%)

Sp (%)

Acc (%)

Str(%)

MCC

Threshold

iGPCR-Drug

80.8

66.9

71.6

73.9

0.45

N/A

OET-KNN

67.7

84.2

78.7

76.9

0.52

0.5

QuickRBF

76.2

77.7

77.2

77.6

0.52

0.45

SVM

76.2

78.9

78.0

77.6

0.53

0.42

RF

78.5

78.1

78.2

78.3

0.54

0.51

RF + PPP

83.1

79.6

80.8

81.3

0.60

0.51

Proposed(Base learner)

83.9

80.0

81.3

81.9

0.61

0.5

Proposed(Ensemble model with Ne = 4)

83.1

82.7

82.8

82.9

0.63

0.5