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Table 1 Correlation between somatic and germline mutation rates by nucleotide context

From: Origins and characterization of variants shared between databases of somatic and germline human mutations

Nucleotide Context

Somatic-Germline Spearman correlation coefficient

P-Value

Trimer

0.71

<  2.2e-16

Trimer, excluding NCG sites

0.65

<  2.2e-16

Pentamer

0.70

<  2.2e-16

Pentamer, controlling for central 3 bases

0.33

<  2.2e-16

Heptamer

0.64

<  2.2e-16

Heptamer, controlling for central 5 bases

0.16

<  2.2e-16

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BMC Bioinformatics

ISSN: 1471-2105

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