Table 1 Performance of the algorithm when the threshold to make a positive prediction was varied
From: Predicting potential adverse events using safety data from marketed drugs
Threshold | FDA-issued safety label changes that were correctly predicted (%) | Predicted safety label changes that were also FDA-issued (%) | Number of adverse events with a high positive predictive value |
|---|---|---|---|
0 | 43 | 13 | 11 |
10 | 39 | 14 | 19 |
30 | 32 | 18 | 28 |
50 | 18 | 28 | 42 |
60 | 17 | 29 | 49 |
70 | 13 | 32 | 53 |
90 | 11 | 34 | 48 |