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Table 3 Comparison among the proposed miRTissue ce database and other 7 ceRNA interactions databases, in terms of their main features

From: miRTissue ce: extending miRTissue web service with the analysis of ceRNA-ceRNA interactions

Features miRTissue ce miRTarBase ceRDB lnCeDB miRSponge LncACTdb miRcode starBase v2.0
ceRNA interaction data sources miRTarBase HMDD TargetScan TargetScan TarBase miRTarBase TargetScan miRBase
  miRCode NCBI   StarBase miRTarBase miRanda   refSeq
  LncACTdb 2.0 RefSeq   miRCode miRanda TarBase   Ensembl database
  miRSponge miRBase    miRecord    TargetScan
   miRanda       Pictar2, miRanda
   TargetScan       PITA, RNA22
ceRNA classes miRNA-mRNA miRNA-mRNA miRNA-mRNA miRNA-mRNA miRNA-mRNA miRNA-mRNA miRNA-mRNA miRNA-mRNA
  miRNA-lncRNA    miRNA-lncRNA miRNA-lncRNA miRNA-lncRNA miRNA-lncRNA miRNA-lncRNA
  miRNA-Pseudogenes     miRNA-Pseudogenes miRNA-Pseudogenes miRNA-Pseudogenes miRNA-Pseudogenes
      miRNA-circRNA miRNA-circRNA   miRNA-circRNA
         RBP-ncRNA
         RBP-mRNA
ceRNA network hypergeometric test N/A N/A hypergeometric test hypergeometric test hypergeometric test N/A hypergeometric test
prediction algorithm +      +   
  global test      Pearson correlation   
  +        
  SPONGE        
TCGA expression profiles Yes No No No No Yes No Yes
for ceRNA interactions         
p-value on Yes No No No No No No No
ceRNA interaction score         
Multiple ceRNA analysis Yes No No No No No No No
Multiple tissue selection Yes No No No No No No Yes
References N/A [17] [25] [27] [30] [34] [29] [28]