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Table 2 The biomarker genes discovered from non-treatment studies along with their regulation and description

From: Computational identification of biomarker genes for lung cancer considering treatment and non-treatment studies

Gene

Regulation

Description

BUB3

UP

BUB3 mitotic checkpoint protein

CCNB1

UP

Cyclin B1

CCNB2

DOWN

Cyclin B2

CDC20

DOWN

Cell division cycle 20

CDCA8

DOWN

Cell division cycle associated 8

CDK1

DOWN

Cyclin-dependent kinase 1

CENPF

UP

Centromere Protein F

CENPI

UP

Centromere Protein I

KIF18A

UP

Kinesin Family Member 18A

KNTC1

UP

Kinetochore Associated 1

MAD2L1

UP

MAD2 mitotic arrest deficient like 1

NDC80

UP

NDC80 Kinetochore Complex Component

NUP37

DOWN

Nucleoporing 37 kDa

PCNA

UP

Proliferating Cell Nuclear Antigen

RAD21

UP

RAD21 homolog

ZWINT

UP

ZW10 Interacting Kinetochore Protein