Table 4 Pathway analysis of 15 gene markers
Ingenuity Canonical Pathways | -Log(P-value) | Ratio | Molecules |
|---|---|---|---|
C21-Steroid Hormone Metabolism | 2.07E00 | 1.41E-02 | HSD11B2 |
Complement System | 1.84E00 | 2.78E-02 | C8B |
Glutathione Metabolism | 1.65E00 | 1.02E-02 | GSTM2 |
PXR/RXR Activation | 1.54E00 | 1.16E-02 | GSTM2 |
Androgen and Estrogen Metabolism | 1.51E00 | 6.99E-03 | HSD11B2 |
Neuregulin Signaling | 1.43E00 | 1E-02 | AREG |
Metabolism of Xenobiotics by Cytochrome P450 | 1.27E00 | 4.76E-03 | GSTM2 |
Aryl Hydrocarbon Receptor Signaling | 1.24E00 | 6.37E-03 | GSTM2 |
NRF2-mediated Oxidative Stress Response | 1.14E00 | 5.41E-03 | GSTM2 |
LPS/IL-1 Mediated Inhibition of RXR Function | 1.1E00 | 4.88E-03 | GSTM2 |
Xenobiotic Metabolism Signaling | 9.73E-01 | 3.4E-03 | GSTM2 |