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Table 2 Software packages and libraries used within VADR

From: VADR: validation and annotation of virus sequence submissions to GenBank

software and website

purpose in VADR

Bio-Easel v0.09 github.com/nawrockie/Bio-Easel

sequence alignment handling and sequence utility functions

Sequip v0.03 github.com/nawrockie/sequip

option handling, output file handling and other utilities

Infernal v1.1.3 github.com/EddyRivasLab/infernal

build and use profile HMMs and CMs to classify, validate, align and annotate sequences

BLAST+ v2.9.0 ftp.ncbi.nlm.nih.gov/blast/executables/blast+/2.9.0

build BLAST databases and validate CDS/protein predictions