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Table 1 Comparison of functionalities of currently available isomiR analysis tools

From: IsomiR_Window: a system for analyzing small-RNA-seq data in an integrative and user-friendly manner

 

Multiple input files

Identification of sncRNAs

Types of IsomiRs

Novel miRNA

DE*

miRNA targets

Functional analysis

GUI

IsomiR Window

▪##

f

CPSS2.0

 

a,b,c

DeAnnIso

  

a,b,c

 

miR-isomiRExp

  

a,b,d

 

   

mirSpring

  

a,b

 

   

IsomiRage

  

a,b

 

   

isomiRID

  

a,b,c,d,e

 

   

miRMOD

  

a,b,d

  

 

Chimira

 

a,b,c,d,e

    

sRNAtoolbox

f

CBS-miRSEQ

a,b

 

CAP-miRSEQ

 

   

UEA- Small RNA Workbench

 

  

  1. *Differential Expression
  2. a3′end modifications; b5′end modifications; cinternal editings; d3′ tailings; einternal SNPs; fall types and fuzzy combinations of isomiRs
  3. ##Produces table with quantification of other types of snRNAs that can be used for differential expression via command line