From: IsomiR_Window: a system for analyzing small-RNA-seq data in an integrative and user-friendly manner
Pathway name | Entities | Reactions | ||||
---|---|---|---|---|---|---|
Found | Ratio | p value | FDR* | Found | Ratio | |
Defective EXT1 causes exostoses 1, TRFS2 and CHDS | 5/16 | 7.87e-04 | 0.026 | 0.996 | 4/4 | 3.25e-04 |
Defective EXT2 causes exostoses 2 | 5/16 | 7.87e-04 | 0.026 | 0.996 | 4/4 | 3.25e-04 |
Defective B3GALT6 causes EDSP2 and SEMDJL1 | 5/21 | 0.001 | 0.067 | 0.996 | 1/1 | 8.12e-05 |
Defective B3GALT7 causes EDS, progeroid type | 5/21 | 0.001 | 0.067 | 0.996 | 1/1 | 8.12e-05 |
Defective B3GAT3 causes JDSSDHD | 5/22 | 0.001 | 0.079 | 0.996 | 1/1 | 8.12e-05 |
Negative regulation of TCF-dependent signaling by DVL-interacting proteins | 2/5 | 2.46e-04 | 0.094 | 0.996 | 2/2 | 1.62e-04 |
Keratan sulfate biosynthesis | 8/39 | 0.002 | 0.11 | 0.996 | 8/9 | 7.31e-04 |
NOTCH2 Activation and Transmission of Signal to the Nucleus | 6/32 | 0.002 | 0.115 | 0.996 | 11/11 | 8.94e-04 |
HS-GAG biosynthesis | 7/40 | 0.002 | 0.121 | 0.996 | 13/14 | 0.001 |
Interleukin-21 signaling | 3/12 | 5.90e-04 | 0.127 | 0.996 | 5/5 | 4.06e-04 |
Phase 3- rapid repolarisation | 3/12 | 5.90-e04 | 0.127 | 0.996 | 2/2 | 1.62e-04 |
O-linked glycosylation of mucins | 11/73 | 0.004 | 0.136 | 0.996 | 17/17 | 0.001 |
Acyl chain remodelling of PS | 6/34 | 0.002 | 0.14 | 0.996 | 4/8 | 6.50e-04 |
WNT ligand secretion is abrogated by PORCN inhibitor LGK974 | 1/2 | 9.84e-05 | 0.185 | 0.996 | 1/1 | 8.12e-05 |
Defective PMM2 causes PMM2-CDG (CDG-1a) | 1/2 | 9.84e-05 | 0.185 | 0.996 | 1/1 | 8.12e-05 |
Defective SLC26A4 causes Pendred syndrome (PDS) | 1/2 | 9.84e-05 | 0.185 | 0.996 | 1/1 | 8.12e-05 |
Acyl chain remodelling of PI | 5/30 | 0.001 | 0.198 | 0.996 | 3/6 | 4.87e-04 |
RNF mutatnts show enhanced WNT signaling and proliferation | 2/8 | 3.93e-04 | 0.199 | 0.996 | 1/1 | 8.12e-05 |
Mitochondrial calcium ion transport | 5/31 | 0.002 | 0.216 | 0.996 | 5/10 | 8.12e-04 |
Retinoid metabolismo and transport | 17/107 | 0.005 | 0.216 | 0.996 | 10/28 | 0.002 |
IRAK1 recruits IKK complex | 3/16 | 7.87e-04 | 0.227 | 0.996 | 4/4 | 3.25e-04 |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | 3/16 | 7.87e-04 | 0.227 | 0.996 | 4/4 | 3.25e-04 |
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | 2/9 | 4.43e-04 | 0.236 | 0.996 | 3/3 | 2.44e-04 |
Erythropoietin activates STAT5 | 2/9 | 4.43e-04 | 0.236 | 0.996 | 3/3 | 2.44e-04 |
STAT5 activation | 2/9 | 4.43e-04 | 0.236 | 0.996 | 3/3 | 2.44e-04 |