TPSC: a module detection method based on topology potential and spectral clustering in weighted networks and its application in gene co-expression module discovery

Table 1 Statistically significant survival difference of modules generated by four methods

Module	Size	Group with increased Survival	p Value (Log-rank test)	q Value (B&H FDR)
TPSC-w (2/13)
G1	518	Downregulated	0.0430	0.2795
G12	261	Upregulated	0.0006	0.0077
TPSC-1 (4/24)
M6	57	Upregulated	0.0460	0.2760
M16	89	Downregulated	0.0250	0.2000
M21	358	Downregulated	0.0150	0.1800
M23	260	Upregulated	0.0120	0.1800
lmQCM (2/13)
Q4	109	Upregulated	0.0019	0.0247
Q7	43	Downregulated	0.0280	0.1820
WGCNA (2/17)
W2	307	Upregulated	0.0130	0.2210
W13	192	Downregulated	0.0490	0.4165

ISSN: 1471-2105