Hyperparameter | Description | Value |
---|---|---|
k | Number of nearest neighbors (Eq. 9) | 20 |
α | Effectiveness of cell line similarity (Eq. 11) | 0.5 |
β | Effectiveness of drug similarity (Eq. 11) | 0.1 |
λc | Variance parameter of cell lines (Eq. 11) | 0.5 |
λd | Variance parameter of drugs (Eq. 11) | 0.5 |
λ | Importance of SimEXP (Eq. 8) | 2 |
γ | Importance of SimCNV (Eq. 8) | 2 |
ϕ | Importance of SimMUT (Eq. 8) | 2 |
ψ | Importance of SimIC50 (Eq. 8) | 5 |
ρ | Importance of SimTISSUE (Eq. 8) | 2 |
threshold | Threshold parameter | 0.4 |