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Table 3 Real data: Comparison of estimation of the number of non-redundant variates from the permutation method (ENT, obtained as the average of the ENT estimates for all the clinical outcomes measures considered via the multivariate Normal and the multivariate log-Normal methods) and via approximation procedures based on the eigenvalues of the correlation matrix of the metabolite concentrations (Meff)

From: Multiple-testing correction in metabolome-wide association studies

  MESA BINNED MESA NOESY MESA CPMG
ENT 352(53.8%) 2744(9.0%) 16014(52.3%)
Meff.MWSL 345(52.7%) 1931(6.3%) 11570(37.8%)
Meff.Galwey [10] 201(30.7%) 524(1.7%) 1815(5.9%)
Meff.Gao [9] 435(66.4%) 2705(8.8%) 3537(11.6%)
Meff.Liji [8] 226(34.5%) 2534(8.3%) 4972(16.3%)
Meff.Nyholt [7] 611(93.3%) 26823(87.7%) 29704(97.1%)
  1. R = ENT/ANT(%) ratio in brackets. ANT = 655 for the MESA BINNED data, and ANT = 30590 for the NOESY and CPMG data. Meff estimates closest to ENT estimates in bold