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Fig. 1 | BMC Bioinformatics

Fig. 1

From: cognac: rapid generation of concatenated gene alignments for phylogenetic inference from large, bacterial whole genome sequencing datasets

Fig. 1

Overview of the cognac algorithm. Whole genome sequences and gene annotations are input, and the coding sequences are extracted and translated to return the amino acid sequences. The amino acid sequences are clustered to identify orthologous genes and the single copy, core genes are extracted from the dataset. For each core gene, unique alleles are identified and aligned and the alignment is parsed to represent the aligned sequence for the full dataset. Alignments are then concatenated, and are ready for downstream analysis

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BMC Bioinformatics

ISSN: 1471-2105

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