Fig. 1
From: Automatic reconstruction of metabolic pathways from identified biosynthetic gene clusters
Overview of the BiGMeC pipeline. a Schematic description of how the BGC annotation file produced by antiSMASH is parsed and used to construct the associated metabolic pathway. b BiGMeC extends the rule-based identification of modules from antiSMASH with bridging modules and analysis of module activity, as exemplified here with this toy BGC: The last module in gene A and the first module in gene B (marked by green edges) constitute an active bridging module that is not identified by antiSMASH [12]. The last module on gene C (red edge color) are most often found to be inactive, a feature currently incorporated into BiGMeC