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Fig. 9 | BMC Bioinformatics

Fig. 9

From: Density Peak clustering of protein sequences associated to a Pfam clan reveals clear similarities and interesting differences with respect to manual family annotation

Fig. 9

Annotation for protein Q06330. a Sequence Pfam annotation; the yellow box marks a hit obtained using the profile-HMM derived from metacluster MC-28_P53. b Pfam and MC-28_P53 annotations of a mapped to one of the available structures of Q06330 (PDBid 3nbn:A). Color code for families and regions is the same as in (A). c Structural alignment between the MC-28_P53’s annotated region of 3nbn (yellow) and the TIG domain of PDB structure 4hw6 (light blue). Alignment obtained with DALI pairwise online tool; alignment features: Z = 6.2, RMSD = 2.2, percent sequence identity = 25

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BMC Bioinformatics

ISSN: 1471-2105

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