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Fig. 5 | BMC Bioinformatics

Fig. 5

From: A machine learning-based gene signature of response to the novel alkylating agent LP-184 distinguishes its potential tumor indications

Fig. 5

Overlap between and functional enrichment of LP-184 correlated genes from training and test sets. a This Venn diagram shows common genes between NCI-60 correlation with actual LP-184 sensitivity, and CCLE correlation with predicted LP-184 sensitivity. Bar charts show common GO enriched categories from b biological process, c cellular component, d molecular function aspects and e signaling pathway from KEGG (Kyoto Encyclopedia of Genes and Genomes), between NCI-60 top correlated genes and CCLE top correlated genes. Top 20 significant (FDR <  = 0.05) GO enrichments were selected for comparison

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BMC Bioinformatics

ISSN: 1471-2105

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