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Fig. 1 | BMC Bioinformatics

Fig. 1

From: The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli

Fig. 1

D1, D2 and D3 E. coli network diagram illustrating differences in their topologies. D1, D2 and D3 models are constituted of 271, 307 and 327 enzymatic reactions and 160, 188 and 197 metabolites, respectively. The reactions (edges) and metabolites (nodes) are coloured according to their pertinence to D1 (blue), D2 (red) and D3 (green). Reaction labels indicate if a reaction is unidirectional (black) or, bidirectional in D1 (blue), D2 (red) and D3 (green). The reactions that are bidirectional in a smaller model were also bidirectional in the larger models. Diagram does not include all the reactions of the systems. Full details of the reactions and metabolites in the models are provided in Additional file 3. yEd Version 3.20.1 was used to generate the network diagram

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