Fig. 3

ROC curves for predicting drug–disease associations. The ROC curve is computed for SAveRUNNER algorithm (light blue curve) and BiRW algorithm (orange curve) by plotting the true positive rate (TPR), i.e., sensitivity placed on Y-axis against the false positive rate (FPR), i.e., 1-specificity placed on X-axis at various threshold settings. Diagonal grey line represents the line of no-discrimination between positive class (known drug-disease associations) and negative class (unknown drug-disease associations)